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| 17 Januari 21 | ||
| Aston Villa | 08:00 | Everton |
| 17 April 21 | ||
| Southampton | 07:00 | Crystal Palace |
| 24 April 21 | ||
| Arsenal | 02:00 | Everton |
| Liverpool | 18:30 | Newcastle United |
| West Ham United | 23:30 | Chelsea |
| 25 April 21 | ||
| Sheffield United | 02:00 | Brighton & Hov… |
| Wolverhampton Wanderers | 18:00 | Burnley |
| Leeds United | 20:00 | Manchester United |
| 26 April 21 | ||
| Aston Villa | 01:00 | West Bromwich Albion |
| 27 April 21 | ||
| Leicester City | 02:00 | Crystal Palace |
| 01 Mei 21 | ||
| Southampton | 02:00 | Leicester City |
| Crystal Palace | 18:30 | Manchester City |
| Brighton & Hov… | 21:00 | Leeds United |
| Chelsea | 23:30 | Fulham |
| 02 Mei 21 | ||
| Everton | 02:00 | Aston Villa |
| Newcastle United | 20:00 | Arsenal |
| Manchester United | 22:30 | Liverpool |
| 03 Mei 21 | ||
| Tottenham Hotspur | 01:15 | Sheffield United |
| 04 Mei 21 | ||
| West Bromwich Albion | 00:00 | Wolverhampton Wanderers |
| Burnley | 02:15 | West Ham United |
| 23 April 21 | ||
| Leicester City | 3 - 0 | West Bromwich Albion |
| 22 April 21 | ||
| Aston Villa | 1 - 2 | Manchester City |
| Tottenham Hotspur | 2 - 1 | Southampton |
| 21 April 21 | ||
| Chelsea | 0 - 0 | Brighton & Hov… |
| 20 April 21 | ||
| Leeds United | 1 - 1 | Liverpool |
| 18 April 21 | ||
| Manchester United | 3 - 1 | Burnley |
| Arsenal | 1 - 1 | Fulham |
| Wolverhampton Wanderers | 1 - 0 | Sheffield United |
| 17 April 21 | ||
| Newcastle United | 3 - 2 | West Ham United |
| Everton | 2 - 2 | Tottenham Hotspur |
| 13 April 21 | ||
| Brighton & Hov… | 0 - 0 | Everton |
| West Bromwich Albion | 3 - 0 | Southampton |
| 12 April 21 | ||
| Sheffield United | 0 - 3 | Arsenal |
| 11 April 21 | ||
| Tottenham Hotspur | 1 - 3 | Manchester United |
| West Ham United | 3 - 2 | Leicester City |
| Burnley | 1 - 2 | Newcastle United |
| 10 April 21 | ||
| Crystal Palace | 1 - 4 | Chelsea |
| Liverpool | 2 - 1 | Aston Villa |
| Manchester City | 1 - 2 | Leeds United |
| Fulham | 0 - 1 | Wolverhampton Wanderers |
| # | Team | MP | W | D | L | F | A | G | P |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Manchester City | 33 | 24 | 5 | 4 | 69 | 24 | +45 | 77 |
| 2 | Manchester United | 32 | 19 | 9 | 4 | 64 | 35 | +29 | 66 |
| 3 | Leicester City | 32 | 18 | 5 | 9 | 58 | 37 | +21 | 59 |
| 4 | Chelsea | 32 | 15 | 10 | 7 | 50 | 31 | +19 | 55 |
| 5 | West Ham United | 32 | 16 | 7 | 9 | 53 | 42 | +11 | 55 |
| 6 | Tottenham Hotspur | 33 | 15 | 8 | 10 | 56 | 38 | +18 | 53 |
| 7 | Liverpool | 32 | 15 | 8 | 9 | 54 | 38 | +16 | 53 |
| 8 | Everton | 31 | 14 | 7 | 10 | 43 | 40 | +3 | 49 |
| 9 | Arsenal | 32 | 13 | 7 | 12 | 44 | 36 | +8 | 46 |
| 10 | Leeds United | 32 | 14 | 4 | 14 | 50 | 50 | +0 | 46 |
| 11 | Aston Villa | 31 | 13 | 5 | 13 | 44 | 35 | +9 | 44 |
| 12 | Wolverhampton Wanderers | 32 | 11 | 8 | 13 | 32 | 41 | -9 | 41 |
| 13 | Crystal Palace | 31 | 10 | 8 | 13 | 33 | 52 | -19 | 38 |
| 14 | Southampton | 32 | 10 | 6 | 16 | 40 | 58 | -18 | 36 |
| 15 | Newcastle United | 32 | 9 | 8 | 15 | 35 | 53 | -18 | 35 |
| 16 | Brighton & Hov… | 32 | 7 | 13 | 12 | 33 | 38 | -5 | 34 |
| 17 | Burnley | 32 | 8 | 9 | 15 | 26 | 45 | -19 | 33 |
| 18 | Fulham | 33 | 5 | 12 | 16 | 25 | 43 | -18 | 27 |
| 19 | West Bromwich Albion | 32 | 5 | 9 | 18 | 28 | 62 | -34 | 24 |
| 20 | Sheffield United | 32 | 4 | 2 | 26 | 17 | 56 | -39 | 14 |